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您的位置：首頁(yè)  /  技術(shù)文章  /  Achem-block 砌塊化學(xué)-相關(guān)技術(shù)文章

Achem-block 砌塊化學(xué)-相關(guān)技術(shù)文章

更新時(shí)間：2024-08-20      瀏覽次數(shù)：309

Achem-block 砌塊化學(xué)

 

chem-Block 成立于 2019 年，已為 80+ 家公司或?qū)W術(shù)界提供可持續(xù)的 BB 服務(wù)（從毫克到公斤級(jí)）。與本地（能源化工等）和國(guó)外（化學(xué)空間等）供應(yīng)商的戰(zhàn)略營(yíng)銷合作確保了結(jié)構(gòu)多樣性和準(zhǔn)時(shí)交貨。

Achem-block基于學(xué)術(shù)期刊的前沿反應(yīng)以及臨床和臨床前藥物的核心結(jié)構(gòu)，設(shè)計(jì)、合成和收集結(jié)構(gòu)多樣化的單體、支架和中間體。對(duì)獨(dú)te和新穎結(jié)構(gòu)的關(guān)注使 BB2.0 系列阿赫姆塊成為您藥物發(fā)現(xiàn)的最佳匹配。

通過(guò)可見(jiàn)光介導(dǎo)的光氧化還原催化活化CDFA和a-鹵代羧酸，從而能夠產(chǎn)生親電和雙功能自由基中間體，其與烯烴的反應(yīng)性可以通過(guò)溶劑系統(tǒng)的性質(zhì)進(jìn)一步調(diào)節(jié)。

利用CDFA或a-鹵代乙酸的簡(jiǎn)單而不同的方案的特點(diǎn)是選擇C–O（內(nèi)酯）、C–N（內(nèi)酰胺）和C–H（HAT）鍵結(jié)構(gòu)。

不需要初始a-鹵代羧酸的預(yù)官能化，利用氯二氟yi酸（CDFA）和a-鹵代羧酸合成g-內(nèi)酯、g-內(nèi)酰胺和a，a-二氟酯已經(jīng)完成了包括生物活性分子在內(nèi)的幾種復(fù)雜框架的合成。

在烯烴分子存在的情況下，該物種作為一種獨(dú)te的雙功能中間體，允許通過(guò)單電子轉(zhuǎn)移（SET）或氫原子轉(zhuǎn)移（HAT）事件在Giese型加合物上形成規(guī)定的C–O、C–N和C–H鍵。

 

Achem-block品牌部分產(chǎn)品訂購(gòu)信息：

CAS

貨號(hào)

規(guī)格

產(chǎn)品名

139393-02-5

CB103756

100mg

(S)-2-Amino-3-(5-cyano-1H-indol-3-yl)propanoic   acid

139393-02-5

CB103756

250mg

(S)-2-Amino-3-(5-cyano-1H-indol-3-yl)propanoic   acid

864070-44-0

ABC-0903625

1g

EMPAGLIFLOZIN

864070-44-0

ABC-0903625

250mg

EMPAGLIFLOZIN

864070-44-0

ABC-0903625

5g

EMPAGLIFLOZIN

53616-34-5

CB000701339

1g

2-(furan-3-yl)ethan-1-ol

53616-34-5

CB000701339

5g

2-(furan-3-yl)ethan-1-ol

1155374-90-5

CB000745337

1g

sodium   2-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetate

1155374-90-5

CB000745337

5g

sodium   2-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetate

1323290-64-7

ABC-0302368

100mg

methyl   4,5-diamino-5-oxopentanoate hydrochloride

1323290-64-7

ABC-0302368

1g

methyl   4,5-diamino-5-oxopentanoate hydrochloride

1323290-64-7

ABC-0302368

250mg

methyl   4,5-diamino-5-oxopentanoate hydrochloride

16642-94-7

ABC-16642B

1g

3-(4-Cyanophenyl)acrylic acid

16642-94-7

ABC-16642B

5g

3-(4-Cyanophenyl)acrylic acid

60706-59-4

CB000742283

1g

3,9-diazaspiro[5.5]undecane-2,4-dione   hydrochloride

60706-59-4

CB000742283

5g

3,9-diazaspiro[5.5]undecane-2,4-dione   hydrochloride

5464-22-2

ABC127599-25g

25g

Tetramethyl   ethane-1,1,2,2-tetracarboxylate

5464-22-2

ABC127599-5g

5g

Tetramethyl   ethane-1,1,2,2-tetracarboxylate

1550684-79-1

CB000719371

1g

methyl   3-bromo-5-chloro-4-fluorobenzoate

1550684-79-1

CB000719371

5g

methyl   3-bromo-5-chloro-4-fluorobenzoate

371764-26-0

CB000752428

1g

(2,2-dimethylpropyl)(2,2,2-trifluoroethyl)amine

371764-26-0

CB000752428

5g

(2,2-dimethylpropyl)(2,2,2-trifluoroethyl)amine

62172-88-7

ACB-EN9247

1g

[2-(methoxymethyl)phenyl]methanol

62172-88-7

ACB-EN9247

5g

[2-(methoxymethyl)phenyl]methanol

52499-93-1

ACB-EN543

1g

2,4,6-trimethoxybenzene-1-sulfonyl   chloride

52499-93-1

ACB-EN543

5g

2,4,6-trimethoxybenzene-1-sulfonyl   chloride

95088-20-3

CBN-05934

100mg

N-(4-Trifloromethybenzyl)cinchoninum   bromide

95088-20-3

CBN-05934

250mg

N-(4-Trifloromethybenzyl)cinchoninum   bromide

95088-20-3

CBN-05934

500mg

N-(4-Trifloromethybenzyl)cinchoninum   bromide

1025796-31-9

ABC-02272B

1g

(S)-DI-TERT-BUTYL   2-(3-((S)-6-AMINO-1-(TERT-BUTOXY)-1-OXOHEXAN-2-YL)UREIDO)PENTANEDIOATE

1025796-31-9

ABC-02272B

250mg

(S)-DI-TERT-BUTYL   2-(3-((S)-6-AMINO-1-(TERT-BUTOXY)-1-OXOHEXAN-2-YL)UREIDO)PENTANEDIOATE

4547-43-7

CB000074720

1g

methyl 6-hydroxyhexanoate

4547-43-7

CB000074720

5g

methyl 6-hydroxyhexanoate

211315-05-8

CB000737953

1g

methyl   2-amino-2-cyclopropylpropanoate hydrochloride

211315-05-8

CB000737953

5g

methyl   2-amino-2-cyclopropylpropanoate hydrochloride

56552-80-8

CBN-05963

5g

1-O-BENZYL-RAC-GLYCEROL

100366-66-3

CBN-05982

1g

6,6-DIBROMO-2,2:6,2-TERPYRIDINE

100366-66-3

CBN-05982

5g

6,6-DIBROMO-2,2:6,2-TERPYRIDINE

685514-01-6

ABC-0302490

100mg

1-(TRIISOPROPYLSILYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-OL

685514-01-6

ABC-0302490

1g

1-(TRIISOPROPYLSILYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-OL

685514-01-6

ABC-0302490

250mg

1-(TRIISOPROPYLSILYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-OL

4430-05-1

CB000744536

1g

1-(4-bromophenyl)-2-(pyridin-2-yl)ethan-1-one

4430-05-1

CB000744536

5g

1-(4-bromophenyl)-2-(pyridin-2-yl)ethan-1-one

19522-96-4

ABC-0622056

100mg

7-BROMO-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE

19522-96-4

ABC-0622056

1g

7-BROMO-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE

19522-96-4

ABC-0622056

250mg

7-BROMO-BENZO[1,3]DIOXOLE-5-CARBALDEHYDE

40133-06-0

ABC-0614360

100mg

5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-2-CARBOXYLIC   ACID

40133-06-0

ABC-0614360

1g

5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-2-CARBOXYLIC   ACID

40133-06-0

ABC-0614360

250mg

5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-2-CARBOXYLIC   ACID

81223-73-6

ABC-1004302

100mg

1-(1H-INDOL-6-YL)ETHANONE

81223-73-6

ABC-1004302

1g

1-(1H-INDOL-6-YL)ETHANONE

81223-73-6

ABC-1004302

250mg

1-(1H-INDOL-6-YL)ETHANONE

1228838-07-0

CB000753748

1g

2-(6-fluoro-1-methyl-1H-1,3-benzodiazol-2-yl)ethan-1-amine   dihydrochloride

1228838-07-0

CB000753748

5g

2-(6-fluoro-1-methyl-1H-1,3-benzodiazol-2-yl)ethan-1-amine   dihydrochloride

858209-27-5

CBN-05967

1g

(4-bromo-2-methylphenyl)hydrazine   hydrochloride

858209-27-5

CBN-05967

5g

(4-bromo-2-methylphenyl)hydrazine   hydrochloride

1171125-20-4

CB00801867

1g

Ethyl   4-bromo-5-methyl-1H-imidazole-2-carboxylate

1171125-20-4

CB00801867

250mg

Ethyl   4-bromo-5-methyl-1H-imidazole-2-carboxylate

1171125-20-4

CB00801867

5g

Ethyl   4-bromo-5-methyl-1H-imidazole-2-carboxylate

1698293-93-4

CBN-05968

10g

2-ISOPROPYL-4-METHYLPYRIDIN-3-AMINE

1698293-93-4

CBN-05968

25g

2-ISOPROPYL-4-METHYLPYRIDIN-3-AMINE

1698293-93-4

CBN-05968

5g

2-ISOPROPYL-4-METHYLPYRIDIN-3-AMINE

42754-96-1

ABC92758-25g

25g

4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine

944900-06-5

ABC234778-1g

1g

2-Chloro-6-(trifluoromethyl)nicotinaldehyde

944900-06-5

ABC234778-5g

5g

2-Chloro-6-(trifluoromethyl)nicotinaldehyde

51154-06-4

ABC117683-10g

10g

(S)-1-(tert-Butoxycarbonyl)-2,5-dihydro-1H-pyrrole-2-carboxylic   acid

51154-06-4

ABC117683-25g

25g

(S)-1-(tert-Butoxycarbonyl)-2,5-dihydro-1H-pyrrole-2-carboxylic   acid

51154-06-4

ABC117683-5g

5g

(S)-1-(tert-Butoxycarbonyl)-2,5-dihydro-1H-pyrrole-2-carboxylic   acid

40611-69-6

ABC-0618007

100mg

METHYL 3-METHYL-1H-PYRROLE-2-CARBOXYLATE

40611-69-6

ABC-0618007

1g

METHYL   3-METHYL-1H-PYRROLE-2-CARBOXYLATE

40611-69-6

ABC-0618007

250mg

METHYL   3-METHYL-1H-PYRROLE-2-CARBOXYLATE

54326-16-8

ABC9390-25g

25g

5-Chloropyrimidin-2(1H)-one

4377-58-6

ABC20834-1g

1g

5-Fluorothiophene-2-carboxylic   acid

4377-58-6

ABC20834-5g

5g

5-Fluorothiophene-2-carboxylic   acid

56523-59-2

ABC55963-1g

1g

15-Bromopentadecanoic acid

56523-59-2

ABC55963-250mg

0.25g

15-Bromopentadecanoic acid

1246761-84-1

ABC-YF003

1g

B-1H-pyrrolo[2,3-b]pyridin-4-ylboronic   acid

1246761-84-1

ABC-YF003

5g

B-1H-pyrrolo[2,3-b]pyridin-4-ylboronic   acid

74844-93-2

ABC139529-5g

5g

(S)-1-tert-Butyl 2-methyl   1H-pyrrole-1,2(2H,5H)-dicarboxylate

2158302-01-1

ABC-YF002

1g

(S)-benzyl   2-(cyanomethyl)piperazine-1-carboxylate

2158302-01-1

ABC-YF002

5g

(S)-benzyl   2-(cyanomethyl)piperazine-1-carboxylate

58546-89-7

CBN-05949

1g

1-BENZOFURAN-5-AMINE

58546-89-7

CBN-05949

5g

1-BENZOFURAN-5-AMINE

1209458-83-2

CBN-05984

250mg

2-Bromo-5-fluoro-1,3-thiazole

1209458-83-2

CBN-05984

500mg

2-Bromo-5-fluoro-1,3-thiazole

89179-60-2

CBN-05948

1g

5-CYCLOPROPYL-1,3,4-OXADIAZOL-2-AMINE

89179-60-2

CBN-05948

250mg

5-CYCLOPROPYL-1,3,4-OXADIAZOL-2-AMINE

89179-60-2

CBN-05948

500mg

5-CYCLOPROPYL-1,3,4-OXADIAZOL-2-AMINE

43038-45-5

CBN-05937

10g

1-NAPHTHHYDRAZIDE

950739-21-6

ABC00763830-10g

10g

5-Bromo-1H-pyrazol-3-amine

950739-21-6

ABC00763830-25g

25g

5-Bromo-1H-pyrazol-3-amine

872509-56-3

ABC-0690296

1g

2,6-DICHLORO-3,5-DIMETHOXYANILINE

872509-56-3

ABC-0690296

250mg

2,6-DICHLORO-3,5-DIMETHOXYANILINE

872509-56-3

ABC-0690296

5g

2,6-DICHLORO-3,5-DIMETHOXYANILINE

133427-08-4

ABC27447-10g

10g

Imidazo[1,2-a]pyridine-8-carboxylic   acid

133427-08-4

ABC27447-25g

25g

Imidazo[1,2-a]pyridine-8-carboxylic   acid

133427-08-4

ABC27447-5g

5g

Imidazo[1,2-a]pyridine-8-carboxylic   acid

952138-13-5

ABC55088-1g

1g

4,7-Dichloro-1,6-naphthyridine

952138-13-5

ABC55088-5g

5g

4,7-Dichloro-1,6-naphthyridine

379228-58-7

CBN-05974

10g

5,7-DIFLUOROQUINAZOLIN-4(3H)-ONE

379228-58-7

CBN-05974

5g

5,7-DIFLUOROQUINAZOLIN-4(3H)-ONE

73604-31-6

CBN-05943

10g

2-PHENOXY-N-METHYLETHYLAMINE   HYDROCHLORIDE

73604-31-6

CBN-05943

25g

2-PHENOXY-N-METHYLETHYLAMINE   HYDROCHLORIDE


CBN-05935

10g

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone


CBN-05935

25g

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone


CBN-05935

5g

1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone

1240595-43-0

CBN-05980

1g

Ethyl 4-amino-5-bromonicotinate

1240595-43-0

CBN-05980

5g

Ethyl 4-amino-5-bromonicotinate

103261-70-7

ABC-3261B

1g

ethyl   benzo[d]thiazole-5-carboxylate

1152617-24-7

ABC-YF001

10g

3-Chloro-4-Iodopyridin-2-Amine

1152617-24-7

ABC-YF001

5g

3-Chloro-4-Iodopyridin-2-Amine

2158301-19-8

ABC-58301B

1g

(S)-2-(piperazin-2-yl)acetonitrile   dihydrochloride

1441392-27-3

CBN-05941

1g

tert-butyl (3R,4R)-3-amino-4-fluoropyrrolidine-1-carboxylate

1441392-27-3

CBN-05941

250mg

tert-butyl   (3R,4R)-3-amino-4-fluoropyrrolidine-1-carboxylate

1441392-27-3

CBN-05941

500mg

tert-butyl   (3R,4R)-3-amino-4-fluoropyrrolidine-1-carboxylate

5959-52-4

ABC8136-10g

10g

3-Amino-2-naphthoic acid

5959-52-4

ABC8136-25g

25g

3-Amino-2-naphthoic acid

2012-29-5

ABC-2120B

1g

2,4-DIIODOPHENOL

600-23-7

ACB-EN6997

1g

methyl hydrogen oxalate

600-23-7

ACB-EN6997

5g

methyl hydrogen oxalate

2107505-65-5

ABC-15722B

1g

Ethyl   5-chloro-1H-pyrrole-3-carboxylate

2107505-65-5

ABC-15722B

250mg

Ethyl   5-chloro-1H-pyrrole-3-carboxylate

1820666-70-3

CB015197002

1g

(2-ethylcyclohexyl)methanamine   hydrochloride

1820666-70-3

CB015197002

5g

(2-ethylcyclohexyl)methanamine   hydrochloride

1680206-12-5

CBN-05950

100mg

(bpy)Cu(CF3)3

1680206-12-5

CBN-05950

250mg

(bpy)Cu(CF3)3

1680206-12-5

CBN-05950

500mg

(bpy)Cu(CF3)3

1188338-67-1

CBN-05939

100mg

methyl 4-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate

1188338-67-1

CBN-05939

250mg

methyl   4-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate

1188338-67-1

CBN-05939

500mg

methyl   4-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate

21544-02-5

CB000760607

1g

2-isocyanato-3-methylfuran

21544-02-5

CB000760607

5g

2-isocyanato-3-methylfuran

 

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